Prevalence and characteristics of Streptococcus pneumoniae "putative serotype 6E" isolates from Asian countries.

Diagn Microbiol Infect Dis. 2014 Sep 6;80(4):334-337. doi: 10.1016/j.diagmicrobio.2014.08.017. [Epub ahead of print]

Prevalence and characteristics of Streptococcus pneumoniae "putative serotype 6E" isolates from Asian countries.

Baek JY1, Park IH2, So TM3, Lalitha MK4, Shimono N5, Yasin RM6, Carlos CC7, Perera J8, Thamlikitkul V9, Hsueh PR10, Van PH11, Shibl AM12, Song JH13, Ko KS14.

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Abstract

The prevalence, antimicrobial susceptibility, and genotypes of Streptococcus pneumoniae "putative serotype 6E" isolates from Asian countries were investigated. A total of 244 S. pneumoniae serogroup 6 isolates obtained from 11 Asian countries were included in this study. Of the 244 serogroup 6 isolates, 101 (41.4%) were typed as "putative serotype 6E," followed by serotypes 6A, 6B, 6C, and 6D (27.0, 20.1, 5.7, and 5.7%, respectively). Multilocus sequence typing revealed that clonal complex (CC) 90, including ST90 and its variants, was the most prevalent clonal group of "putative serotype 6E" isolates (n = 63; 62.4%). CC146 and CC315 were also found frequently in some of the countries. Most of the "putative serotype 6E" isolates showed very high resistance rates against cefuroxime, erythromycin, azithromycin, clarithromycin, clindamycin, and trimethoprim/sulfamethoxazole, probably due to their highly resistant to antimicrobials clone, CC90. Our results indicate that "putative serotype 6E" is prevalent in Asian countries. The clonal dissemination of "putative serotype 6E" isolates was also identified.

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KEYWORDS:

CC90; Pneumococci; Serogroup 6

PMID: 25439447 [PubMed - as supplied by publisher]